Julian Gomez-Cambronero Selected Research

Neoplasms (Cancer)

1/2020	Phospholipase D and the Mitogen Phosphatidic Acid in Human Disease: Inhibitors of PLD at the Crossroads of Phospholipid Biology and Cancer.
1/2019	Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment.
1/2018	How miRs and mRNA deadenylases could post-transcriptionally regulate expression of tumor-promoting protein PLD.
1/2018	Lack of effective translational regulation of PLD expression and exosome biogenesis in triple-negative breast cancer cells.
2/2017	A feedback mechanism between PLD and deadenylase PARN for the shortening of eukaryotic poly(A) mRNA tails that is deregulated in cancer cells.
7/2016	A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis.
1/2016	A Repertoire of MicroRNAs Regulates Cancer Cell Starvation by Targeting Phospholipase D in a Feedback Loop That Operates Maximally in Cancer Cells.
1/2016	Down-regulation of MicroRNAs (MiRs) 203, 887, 3619 and 182 Prevents Vimentin-triggered, Phospholipase D (PLD)-mediated Cancer Cell Invasion.
1/2016	PLD-Specific Small-Molecule Inhibitors Decrease Tumor-Associated Macrophages and Neutrophils Infiltration in Breast Tumors and Lung and Liver Metastases.
1/2016	The transcription factors Slug (SNAI2) and Snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion.

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Julian Gomez-Cambronero Research Topics

Disease

24	Neoplasms (Cancer) 01/2020 - 01/2008
13	Breast Neoplasms (Breast Cancer) 01/2018 - 05/2010
8	Neoplasm Metastasis (Metastasis) 01/2018 - 04/2013
6	Inflammation (Inflammations) 12/2020 - 12/2003
4	Infections 01/2020 - 01/2012
2	Atherosclerosis 01/2018 - 01/2018
2	Starvation 01/2018 - 01/2016
2	Carcinogenesis 05/2014 - 01/2014
1	Triple Negative Breast Neoplasms 01/2018
1	Atherosclerotic Plaque (Atheroma) 01/2018
1	Acute Lung Injury 01/2018
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2018
1	Virus Diseases (Viral Diseases) 03/2015
1	Epilepsy (Aura) 02/2015
1	Parasitic Diseases (Parasitic Disease) 05/2013
1	Acute Promyelocytic Leukemia 01/2012
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2011
1	Leukemia 06/2005
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 12/2003

Drug/Important Bio-Agent (IBA)

24	1-dodecylpyridoxal (PLD)IBA 01/2020 - 06/2005
16	Phospholipase DIBA 12/2020 - 07/2010
9	Phosphatidic Acids (Phosphatidic Acid)IBA 01/2020 - 04/2013
8	Protein Isoforms (Isoforms)IBA 01/2020 - 06/2005
6	phospholipase D2IBA 01/2019 - 01/2008
5	Phospholipases (Phospholipase)IBA 01/2018 - 01/2013
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2012
5	EnzymesIBA 01/2018 - 03/2015
4	Phosphotransferases (Kinase)IBA 01/2014 - 05/2010
3	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020 - 01/2015
3	MicroRNAs (MicroRNA)IBA 01/2018 - 01/2016
2	Messenger RNA (mRNA)IBA 01/2018 - 02/2017
2	Phenobarbital (Luminal)FDA Link 01/2018 - 10/2015
2	Epidermal Growth Factor (EGF)IBA 07/2016 - 05/2011
2	ErbB Receptors (EGF Receptor)IBA 10/2015 - 09/2015
2	Lipase (Acid Lipase)FDA Link 02/2015 - 01/2012
2	GTP Phosphohydrolases (GTPases)IBA 05/2013 - 01/2012
2	Monomeric GTP-Binding ProteinsIBA 05/2013 - 07/2010
1	MitogensIBA 01/2020
1	oxidized low density lipoproteinIBA 01/2018
1	LipidsIBA 01/2018
1	CholesterolIBA 01/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	VimentinIBA 01/2016
1	LuciferasesIBA 01/2016
1	Snail Family Transcription FactorsIBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	LigandsIBA 09/2015
1	TubulinIBA 02/2015
1	Aurora Kinase AIBA 02/2015
1	Focal Adhesion Protein-Tyrosine KinasesIBA 02/2015
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 05/2014
1	Small Interfering RNA (siRNA)IBA 05/2013
1	Tyrosine (L-Tyrosine)FDA Link 04/2013
1	Guanosine Triphosphate (GTP)IBA 01/2012
1	Guanosine Diphosphate (GDP)IBA 01/2012
1	MetalsIBA 01/2012
1	CobaltIBA 01/2012
1	IsoenzymesIBA 01/2012
1	Janus Kinase 3IBA 05/2011
1	Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA 12/2003
1	Chemotactic FactorsIBA 12/2003
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2003

Therapy/Procedure

3	Therapeutics 01/2020 - 08/2014
1	Drug Therapy (Chemotherapy) 01/2012